患者,男,36岁。10年前起无明显诱因出现口腔粘膜溃疡,以齿龈及颊粘膜为重。疼痛影响进食,同时伴有阴茎龟头多处溃疡,颜面皮肤里结节样改变,且多处毛囊炎,服用维生素B_2等药物无效。经长春208医院诊为“白塞综合征”。10年来一直服用强的松治疗,每日10mg,一旦停药,上述症状即刻复发。症状复发后强的松剂量需增至每日 Patient, male, 36 years old. 10 years ago no obvious incentive to appear oral mucosal ulcer, with gums and buccal mucosa as the most important. Pain affect eating, accompanied by multiple glans penis ulcer, facial skin nodular change, and multiple folliculitis, taking vitamin B_2 and other drugs ineffective. 208 Changchun Hospital diagnosed as “Behcet’s syndrome.” 10 years has been taking prednisone treatment, daily 10mg, once the withdrawal, the symptoms of the recurrence. The dose of prednisone should be increased daily after symptoms recurrence