作者对选自文献中20例和来自临床的19例的天疱疮患者,作详细研究,观察疾病的活动性与抗体滴度的关系,临床上选择标准,为对四种血清抗体滴度测定多次,随访至少一年.每个病例间接免疫荧光滴度与临床疾病活动性曲线相对照.疾病活动性的等级如下:(+)表示疾病仅限于口腔粘膜或只占整体皮肤10%,而功能良好;(++)口腔粘膜加皮肤损害或皮疹占体表面25%及轻度功能障碍 The authors selected 20 patients from the literature and 19 from the clinical pemphigus patients for detailed study to observe the relationship between disease activity and antibody titer, clinical selection criteria for the four serum antibody titers Multiple follow-up of at least one year. Indirect immunofluorescence titers for each case were compared with clinical disease activity curves. The levels of disease activity are as follows: (+) indicates that the disease is confined to the oral mucosa or only 10% of the total skin, whereas Good function; (++) oral mucosa plus skin lesions or rash 25% of the total body surface and mild dysfunction