本文共观察75只雄性 Wistar 大白鼠,除测其腹部皮下胆固醇肉芽肿重量及总胆固醇含量外,还作血清溶菌酶活性及肺、腹腔巨噬细胞吞菌功能检查,部分动物并肉芽肿电镜等形态观察。结果表明:口服中药蒲黄能激活体内单核—巨噬细胞系统,有利于肉芽肿中脂质的吸收,故加强单核一巨噬细胞系统,可能有助于动脉粥样硬化病变的消退。 A total of 75 male Wistar rats were observed in this study. In addition to measuring the weight and total cholesterol content of subcutaneous cholesterol granuloma in the abdomen, serum lysozyme activity and macrophage function tests in the lung and peritoneal cavity were also performed. Some animals and granuloma electron microscopes were examined. Morphological observations. The results showed that oral administration of Puhuang can activate the mononuclear-macrophage system in vivo, which is beneficial to the absorption of lipids in granuloma. Therefore, strengthening the monocyte-macrophage system may contribute to the regression of atherosclerotic lesions.