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本研究对比6种当前应用的半自动软件包在确定发现肺结节增长所需最小改变的CT肺结节容积的变异。该研究得到伦理委员会批准。为了模拟零增长的随访检查,对20例肺转移病人进行2次低剂量非增强CT扫描。检查之间病人上下检查床。应用6种结节评估软件包评价2次检查所有肺结节的容积。计算足够区分结节视觉可见改变的分割点的变异性(Bland-Altman图的95%CI的上限)。评估214个结节(平均直径10.9mm,范围3.3～30mm)。
This study compared the variability of six currently used semiautomatic software packages in determining the volume of CT lung nodules that is the smallest change necessary to detect increased lung nodules. The study was approved by Ethics Committee. To simulate a zero-growth follow-up examination, two low-dose non-contrast CT scans of 20 patients with lung metastases were performed. Check the patient between the upper and lower bed. Six nodular assessment packages were evaluated for 2 examinations of all lung nodules volumes. Variability of segmentation points (upper 95% CI of Bland-Altman plots) was calculated to be sufficient to distinguish nodule visually visible changes. 214 nodules were evaluated (average diameter 10.9 mm, range 3.3 to 30 mm).