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目的了解西北地区某职工人群的血脂异常现状及其影响因素。方法收集某公司2006~2014年体检资料,分析职工血脂异常情况。结果共收集12 664名职工体检资料。男性血脂异常率明显高于女性(P<0.01),且随年龄的增长有上升趋势。血脂异常主要以总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)异常增高为主,检出率依次为5.77%、25.63%、5.52%。高血压、空腹血糖、体质指数(BMI)在不同分级的血脂异常水平有统计学差异(P<0.01),但高密度脂蛋白胆固醇(HDL-C)与高血压分级不相关(P>0.05)。非条件Logistic回归分析发现,BMI、年龄和空腹血糖的增高是TC、TG、LDL-C的危险因素,男性或汉族人群中TG偏低;而年龄和BMI的偏低是HDL-C保护因素,已婚或女性人群中HDL-C偏低。结论采取多种健康干预措施,降低血脂异常的检出率,是控制高血压、糖尿病等与之密切相关疾病发病率的关键措施。
Objective To understand the status of dyslipidemia and its influencing factors in a worker population in Northwest China. Methods The physical examination data of a company from 2006 to 2014 were collected to analyze the dyslipidemia of employees. Results A total of 12 664 employee physical examination data were collected. The rate of dyslipidemia in men was significantly higher than that in women (P <0.01), and increased with age. The main dyslipidemia was the abnormal increase of total cholesterol (TC), triglyceride (TG) and low density lipoprotein cholesterol (LDL-C), the detection rates were 5.77%, 25.63% and 5.52% respectively. Hypertension, fasting blood glucose and body mass index (BMI) had statistical significance (P <0.01), but high density lipoprotein cholesterol (HDL-C) was not associated with hypertension grade (P> 0.05) . Non-conditional logistic regression analysis showed that the increase of BMI, age and fasting blood glucose were risk factors of TC, TG and LDL-C, while TG was lower in male or Han people; while lower age and BMI were the protective factors of HDL- HDL-C is low in married or females. Conclusions Taking various health interventions to reduce the detection rate of dyslipidemia is the key measure to control the incidence of closely related diseases such as hypertension and diabetes mellitus.