OBJECTIVE: Integrative medicine refers to ongoing efforts to combine the best of conventional and evidence-based complementary therapies. While this effort for colaboration is increasing, traditional complementary and altative medicine (TM-CAM) remains poorly integrated into the current healthcare system of Ghana. At present, it is not clear if practitioners of mainstream medicine favor integrative medicine. The present study, therefore, sought to explore the perceptions of conventional healthcare professionals on integrative medicine. METHODS: A qualitative design composed of semi-structured interviews was conducted with 23 conventional healthcare professionals comprising pharmacists, physicians, nurses and dieticians from two quasi-govment hospitals in Accra, Ghana. RESULTS: Participants’ knowledge of TM-CAM was low, and although they perceived altative medicine as important to current conventional healthcare in Ghana, they expressed anxieties about the potential negative effects of the use of TM-CAM. This paradox was found to account for the low levels of use among these professionals, as wel as the low level of recommendation to their patients. The practitioners surveyed recommended that altative medicine could be integrated into mainstream alopathic healthcare in Ghana through improving knowledge, training as wel as addressing concs of safety and effi cacy. These fi ndings are discussed under the themes: the knowledge gap, the paradox of TM-CAM, experience of use and prescription, and guided integration. We did not observe any differences in views among the participants. CONCLUSION:The conventional healthcare professionals were ready to accept the idea of integrative medicine based on knowledge of widespread use and the potential role of TM-CAM products and practices in improving healthcare delivery in the country. However, to achieve an institutional integration, practitioners’ understanding of TM-CAM must be improved, with specifi c attention to issues of safety, regulation and evidence-based practice of TM-CAM products and services in Ghana.