本文介绍了以溴化钾压片法测定环磷酰胺粉针剂、片剂的红外光谱法。以1050cm~(-1)(P-O-C键)为测定吸收带,按基线法求取不同浓度的吸收度直接制作标准曲线并由此求取样品含量,方法操作简便、专一、重现性好,平均回收率为97.3％,标准差:1.92％,变异系数:4.52％。 This article describes the potassium bromide tablet method for the determination of cyclophosphamide powder injection, tablet infrared spectroscopy. The absorption band was determined by 1050cm -1 POC bond, and the standard curve was obtained directly according to the absorption of different concentrations by the baseline method. The method was simple, simple, specific, reproducible, The average recovery was 97.3%, standard deviation: 1.92%, coefficient of variation: 4.52%.