论文部分内容阅读
Objective To study the chemical constituents of Stephania hernandifolia.Methods Various chromato-graphic techniques were used to isolate the constituents,and the structures were elucidated on the basis of HR-EI-MS,1D-NMR and 2D-NMR spectral analyses.Results A hasubanan alkaloid,hernsubanine D(1)was isolated from the whole plants of S.hernandifolia.The compound was screened for the cytotoxic activity against two human cancer cell lines in vitro.Conclusion Compound 1 is a new compound without cytotoxicity against A549 and K562 cells.
Objective To study the chemical constituents of Stephania hernandifolia. Methods Various chromato-graphic techniques were used to isolate the constituents, and the structures were elucidated on the basis of HR-EI-MS, 1D-NMR and 2D-NMR spectral analyzes. Results A hasubanan alkaloid, hernsubanine D (1) was isolated from the whole plants of S.hernandifolia. The compound was screened for the cytotoxic activity against two human cancer cell lines in vitro. Conlusion Compound 1 is a new compound without cytotoxicity against A549 and K562 cells .