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本文报道观察阿魏酸钠对冠心病患者血小板功能影响的结果,表明阿魏酸钠在体外可显著抑制血小板聚集及血小板 TXA_2生成,其作用呈浓度依赖型。阿魏酸钠4mg/kg 静脉滴注未观察到对冠心病患者血小板功能有显著影响,可能与剂量不足有关。
This article reports the effect of sodium ferulate on platelet function in patients with coronary heart disease, indicating that sodium ferulate can significantly inhibit platelet aggregation and platelet TXA_2 production in vitro, and its effect is concentration-dependent. Sodium ferulate 4mg / kg intravenous infusion was not observed in patients with coronary heart disease have a significant effect on platelet function, may be related to inadequate doses.