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近年来,灭滴灵主要用在治疗腹腔内厌氧菌感染,伦敦的圣妥马斯医院也将该药用于腹腔外厌氧菌感染。本文报告其详情。一、骨和关节的感染:共7例,其中5例是化脓性关节炎,2例是慢性骨髓炎。7例均分离出厌氧菌,并用灭滴灵治疗3周到3个月,除1例外,全部痊愈。7例中除1例外均同时做外科治疗如引流,死骨剔除和手术探查等。值得指出的是1例未作外科治疗,单用灭滴灵;1例手术探查2次无效后改用灭滴灵,这两例都迅速好转。二、原发性肺
In recent years, metronidazole is mainly used in the treatment of intra-abdominal anaerobic infections, St. Stephen’s Hospital in London, the drug will also be used for anaerobic abdominal infection. This article reports the details. First, the bone and joint infections: a total of 7 cases, of which 5 cases of suppurative arthritis, 2 cases of chronic osteomyelitis. Anaerobic bacteria were isolated in 7 cases and treated with metronidazole for 3 weeks to 3 months, except for 1 case, all were cured. In 7 cases, all except one case, surgical treatment was performed at the same time, such as drainage, sequestrum elimination and surgical exploration. It is worth pointing out that 1 case was not treated surgically, metronidazole alone; 1 case of surgical exploration after 2 invalid metronidazole, both of which were rapidly improved. Second, primary lung