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目的分析2014─2016年甘肃省华亭县人间布鲁杆菌病的流行特征,为制定有效的防控措施提供科学依据。方法在布鲁杆菌病疑似病例及密切接触者中开展流行病学调查,并采集被调查者血标本进行虎红平板凝集试验(RBPT)和试管凝集试验(SAT),诊断标准参照《布鲁杆菌病诊断标准》WS 269-2007要求,以描述流行病学方法分析数据。结果 2014─2016年在华亭县对773人进行了血清学检测,检出阳性184人、阳性率23.80%,各年度阳性率差异有统计学意义(χ~2=8.83,P<0.05);策底镇阳性率最高(37.31%),上关乡最低(15.22%),各乡(镇)差异有统计学意义(χ~2=18.41,P<0.05);男性阳性率(27.73%)高于女性(18.62%),差异有统计学意义(χ~2=8.67,P<0.05);阳性者集中在20岁以上年龄组,40~69岁组阳性率最高,70岁~组略有降低,差异有统计学意义(χ~2=26.88,P<0.05);农民阳性率最高(27.20%),其次是畜牧兽医(15.00%)、工人(10.00%)和学生(7.02%),职业差异亦有统计学意义(χ~2=27.06,P<0.05)。结论华亭县人间布鲁杆菌病血清学阳性率呈逐年上升趋势,布鲁杆菌病的防控形式十分严峻,应进一步建立健全卫生和畜牧部门联防联控的工作机制,加大健康教育和动物疫病检疫力度,提高养殖户的防范意识,防止人间布鲁杆菌病进一步蔓延。
Objective To analyze the epidemiological characteristics of human brucellosis in Huating County, Gansu Province from 2014 to 2016, and provide a scientific basis for effective prevention and control measures. Methods The epidemiological investigation was carried out among suspected brucellosis cases and close contacts, and the blood samples of the respondents were collected for the RBPT test and the test tube agglutination test (SAT). The diagnostic criteria were as follows: Diagnostic Criteria for Disease "WS 269-2007, Describing Epidemiological Methods. Results A total of 773 people were tested serologically in Huating County from 2014 to 2016, with a positive rate of 23.80%. The positive rate of each year was significantly different (χ ~ 2 = 8.83, P <0.05). The highest positive rate was 37.31% in the end of the town, the lowest was 15.22% in Shangguan Township, and the difference was statistically significant among all townships (χ ~ 2 = 18.41, P <0.05). The positive rate of male was 27.73% Female (18.62%), the difference was statistically significant (χ ~ 2 = 8.67, P <0.05); positive were concentrated in the age group of over 20 years old, 40-69 years old group the highest positive rate, 70 years old ~ The difference was statistically significant (χ ~ 2 = 26.88, P <0.05). The positive rate of peasants was the highest (27.20%), followed by that of animal husbandry and veterinary (15.00%), workers (10.00%) and students There was statistical significance (χ ~ 2 = 27.06, P <0.05). Conclusion The prevalence of brucellosis in Huating County is increasing year by year. The prevention and control of brucellosis is very serious. The working mechanism of joint prevention and control of health and livestock husbandry should be further established and health education and animal epidemics should be strengthened Quarantine efforts to raise awareness of farmers to prevent and prevent human brucellosis further spread.