Global change has become a hot spot in Quaternary geology, and high|precision, high|sensitivity dating is also an urgent problem which needs to be solved. This paper presents some achievements in U|series dating of marine corals by thermal ionization mass spectrometry (TIMS) and its application to the study of paleo|environments. Recently, coral samples were determined for their ages on a MAT|262 mass spectrometer and satisfactory results have been obtained. Global change has become a hot spot in Quaternary geology, and high | precision, high | sensitivity dating is also an urgent problem which needs to be solved. This paper presents some achievements in U | series dating of marine corals by thermal ionization mass spectrometry (TIMS) and its application to the study of paleo | environments. Recently, coral samples were determined for their ages on a MAT | 262 mass spectrometer and satisfactory results have been obtained.