本文对心得宁硬化性腹膜炎的病因、早期诊断、预防、处理等作了综述。此副作用的主要病变为小肠腹膜脏层与壁层,广泛的纤维化增生反应,可导致肠梗阻。其机理尚未确定,一般认为与它的β阻断作用无关,可能是一种严重的自身免疫性疾病。对心得宁的应用,应该避免长期使用。即使短期给药,也须密切注意此合并症的发生。对可疑病例,及早做胃肠钡餐检查,可期获得早期诊断。已确诊者,首先停药,给予支持疗法,必要时进行手术处理。 This article reviewed the etiology, early diagnosis, prevention and treatment of dexamethasone-induced peritonitis. The main lesion of this side effect is the visceral and parietal layers of the peritoneum, a wide range of fibrotic proliferative reactions can lead to intestinal obstruction. The mechanism has not been established, it is generally believed that its beta blockade has nothing to do, may be a serious autoimmune disease. On the application of decency, should avoid long-term use. Even short-term administration, should pay close attention to the occurrence of this complication. Suspicious cases of early gastrointestinal barium meal examination can be obtained early diagnosis. Have been diagnosed, the first withdrawal, to give supportive therapy, if necessary, surgical treatment.