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目的 :研究高原地区进展期胃癌 (AGC)患者的红细胞免疫功能和淋巴细胞免疫功能 ;方法 :分别对我科住院手术治疗的 32例进展期胃癌患者作了红细胞C3b受体花环 (RBC -C3bRR)、红细胞免疫复合物花环 (RBC -ICR)及淋巴细胞亚群CD3、CD4、CD8、CD4/CD8的检测 ,并与 2 0例正常人结果进行比较 ;结果 :高原地区进展期胃癌患者RBC -C3bRR、CD3、CD4、CD8、CD4/CD8比值均低于正常人 (P <0 .0 1 ) ,RBC -ICR高于正常人 (P <0 .0 1 ) ;结论 :高原地区进展期胃癌患者红细胞免疫系统与淋巴细胞免疫系统均处于抑制状态 ,2个免疫系统的改变有着密切的联系 ,对高原地区进展期胃癌患者应给予免疫支持。
Objective: To study red cell immune function and lymphocyte immune function in patients with advanced gastric cancer (AGC) in high altitude area. Methods: RBC C3b receptor garlands (RBC-C3bRR) were performed in 32 patients with advanced gastric cancer treated in our department. , RBC-ICR and lymphocyte subsets CD3, CD4, CD8, CD4/CD8 were detected and compared with those of 20 healthy subjects; Results: RBC-C3bRR in patients with advanced gastric cancer in plateau areas The ratios of CD3, CD4, CD8 and CD4/CD8 were all lower than normal (P <0.01), and RBC-ICR was higher than normal (P <0.01). Conclusion: Erythrocytes from patients with advanced gastric cancer in plateau Both the immune system and the lymphocyte immune system are in a suppressive state, and the changes in the two immune systems are closely linked. Immune support should be given to patients with advanced gastric cancer in plateau areas.