原发于脾脏的恶性淋巴瘤较为少见,我院1964～1989年共2例,报告如下。例1 男,46岁。因左上腹疼痛50天,于1989年5月以“脾肿大(脾肿瘤)”入院。50天前,偶尔出现左上腹针刺样疼痛,以吸气时为甚。近20天来,疼痛转移至左髂旁,并加剧,无发热、乏力。曾有血吸虫病史。体检:左上腹可及脾肿大平脐,边钝、压痛、表面不平。全身浅表淋巴结无肿大,心肺无殊,肝肋下未及。体温、脉搏、血压、呼吸均正常。实验室检查:Hb 118.9g/L,WBC10.4×10~9/L,N 84％,L16％,血小板总数163×10~9/L,出血、凝血时间正常。骨髓穿刺:有核细胞增生活跃,粒:红=2.86:1,网状细胞计数偏高。B超提示:巨脾,脾内实质性占位病变。术中所见:脾脏明显增大,表 Primary malignant lymphoma in the spleen is relatively rare, our hospital from 1964 to 1989 a total of 2 cases, the report is as follows. Example 1 male, 46 years old. Because of the left upper quadrant pain for 50 days, in May 1989 to “splenomegaly (splenic tumor)” admission. 50 days ago, occasional acupuncture-like pain in the left upper quadrant, to inspiratory even more. Nearly 20 days, the pain transferred to the left iliac and aggravating, no fever, fatigue. There was a history of schistosomiasis. Physical examination: left upper quadrant spleen and flat umbilical, blunt, tender, uneven surface. Systemic superficial lymph nodes without swelling, cardiopulmonary no special, liver and ribs have not. Body temperature, pulse, blood pressure, breathing are normal. Laboratory tests: Hb 118.9g / L, WBC 10.4 × 10 ~ 9 / L, N 84%, L16%, total platelets 163 × 10 ~ 9 / L, bleeding, coagulation time is normal. Bone marrow puncture: nucleated cell hyperplasia, grain: red = 2.86: 1, reticulocyte count is high. B-Tip: splenomegaly, splenic mass lesions. See intraoperative findings: spleen increased significantly, the table