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目的：观察甲状腺局部注射利美达松治疗突眼性甲状腺肿（ＧＤ）的疗效。方法：ＧＤ病人４２例（男性４例，女性３８例，年龄３６±ｓ１１ａ）为治疗组，另４５例为对照组（男性５例，女性４０例，年龄３４±１０ａ），前者在抗甲状腺药物治疗基础上，行利美达松甲状腺局部注射，２．５～５ｍｇ／次，１次／２ｗｋ，４次为一个疗程，治疗１～２个疗程。对照组仅行抗甲状腺药物治疗。结果：治疗组与对照组比较：前者甲状腺体积明显缩小，且质地变软；Ｔ３，Ｔ４，及ＴＳＨ复原时间缩短；病理显示甲状腺内淋巴细胞浸润明显减少，均Ｐ＜０．０１。无明显激素样副作用。结论：利美达松可作为治疗ＧＤ良好的辅助用药
Objective: To observe the efficacy of local thyroid injection of lemethasone in the treatment of exophthalmos goiter (GD). Methods: Forty-two GD patients (4 males, 38 females, age 36 ± s11a) were treated and the other 45 were control group (5 males and 40 females, age 34 ± 10a). The former was treated with antithyroid drugs On the basis of the treatment, the local injection of leymusadine thyroid, 2.5 ~ 5mg / time, 1 / 2wk, 4 times for a course of treatment, treatment of 1 to 2 courses. Control group only anti-thyroid drug treatment. Results: Compared with the control group, the thyroid volume of the former group was significantly reduced and the texture was soft. The recovery time of T3, T4 and TSH was shortened. The pathological changes of thyroid lymphocytes were significantly reduced (P <0.01). No obvious hormone-like side effects. Conclusion: Lemethasone can be used as a good adjuvant for the treatment of GD