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近来,透析患者丙型肝炎病毒(HCV)感染已引起人们的重视。抗-HCV 抗体血清学测定的进展,更提高了人们对这种疾病自然史及流行史的认识。对象和方法采用 HCV-C100抗原的酶联免疫测定法(ELISA)检测系统研究177例长期透析患者中抗-HCV 抗体的流行情况。分析患者检测结果与其年龄、血液透析时间、输血次数、反复多源输血及原先做过肾移植手术的关系。并在15年的回颐性研究中,每3个月测定1次血清转氨酶水平,如超过正常值上限的2倍则有意义。
Recently, hepatitis C virus (HCV) infection in dialysis patients has attracted much attention. The progress of anti-HCV antibody serology has raised people’s awareness of the natural history and prevalence of this disease. Subjects and Methods The prevalence of anti-HCV antibodies in 177 long-term dialysis patients was assayed by enzyme linked immunosorbent assay (ELISA) using the HCV-C100 antigen. Analysis of patient test results and its age, hemodialysis time, the number of transfusions, repeated multi-source blood transfusions and the original renal transplant surgery. In 15 years of follow-up study, serum aminotransferase levels measured once every 3 months, such as more than 2 times the upper limit of normal is meaningful.