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目的 为了加速控制麻疹。方法 安徽省1997 年度对三个地市1 ~6 岁儿童进行麻疹疫苗( M V) 强化免疫,并随后开展了全省麻疹监测。应用酶联免疫吸附法( E L I S A) 检测麻疹、风疹 Ig M 抗体,微量血凝抑制试验检测麻疹 Ig G 抗体。结果 强化免疫后麻疹抗体阳性率上升到100 % , G M T 从1∶18 .97 增长到1 ∶43 .45 ;1998 年上半年麻疹发病数比1997 年同期下降了87 .71 % ,并控制了爆发,检测181 例发热出疹性病例的血清, 其中麻疹 Ig M 阳性105 例,占58 .01 % ,风疹 Ig M 阳性32 例,占17 .68 % 。结论 在保持高水平的 M V 常规免疫时,开展麻疹疫苗强化免疫,建立并逐步完善麻疹监测系统,加强风疹预防工作,是加速控制麻疹的重要策略。
Purpose To speed control of measles. Methods In 1997, Anhui province conducted measles vaccine (M V) immunization against children aged 1-6 in three cities and municipalities, and subsequently conducted a surveillance program on measles across the province. Measles and rubella Ig M antibody were detected by enzyme-linked immunosorbent assay (ELISA) and measles Ig G antibody by micro-hemagglutination inhibition test. Results After the boost, the positive rate of measles antibody rose to 100%, G M T from 1:18. 97 to 1: 43. 45; the incidence of measles in the first half of 1998 decreased by 87 over the same period of 1997. 71%, and control of the outbreak, detection of 181 cases of fever and rash cases of serum, including measles IgM-positive in 105 cases, accounting for 58. 01%, rubella Ig M positive in 32 cases, accounting for 17. 68%. Conclusion It is an important strategy to speed up the control of measles when carrying out the routine immunization of M V at high levels to strengthen the immunity against measles, establish and gradually improve the monitoring system of measles and strengthen the prevention of rubella.