目的　对宫颈未成熟延期妊娠的引产方式进行前瞻性研究 ,以降低过期妊娠发病率和围产儿死亡率。方法　收集我院 1998年 12月至 1999年 12月宫颈未成熟延期妊娠的待产妇 15 0例 ,随机分为 A组 (n=5 0 )、B组 (n=5 0 )及 C级 (n=5 0 )。A、B、C三组分别予以米非司酮、雌三醇及微量缩宫素作预治疗 ,促宫颈成熟。预治疗后 2 4小时 ,缩宫素滴注法引产 ,三组同。结果　 A、B、C三组宫颈评分 :治疗前分别为 4.3± 0 .5、5 .0± 0 .6、4.5± 0 .5 ,P>0 .0 5。治疗后分别为 8.5± 1.1、6 .3± 0 .8、6 .1± 0 .8,P<0 .0 5。引产成功率 A、B、C三组分别为 92 .0 %、74.0 %、70 .0 % ,P<0 .0 5。分娩总产程分别为 10 .4± 1.3、18.7± 2 .3、17.1± 2 .1,P<0 .0 5。而失血量与 Apgar评分三组无差异 ,P>0 .0 5。结论　米非司酮不仅有效地促宫颈成熟 ,并能提高引产成功率 ,且方法简单、安全、无副作用 Objective To conduct a prospective study on the induction of labor in immature pregnant women with delayed pregnancy to reduce the incidence of postpartum pregnancy and perinatal mortality. Methods A total of 150 pregnant women with unexplained postpartum pregnancy were collected from December 1998 to December 1999 in our hospital. Patients were randomly divided into group A (n = 50), group B (n = 50), and group C = 5 0). A, B, C three groups were given mifepristone, estriol and trace oxytocin for pretreatment, promote cervical maturation. 24 hours after pretreatment, oxytocin instillation method, the same three groups. Results A, B, C three groups of cervical score: before treatment were 4.3 ± 0.5,5. 0 ± 0 .6,4.5 ± 0 .5, P> 0. After treatment were 8.5 ± 1.1,6 .3 ± 0 .8,6 .1 ± 0 .8, P <0. The success rates of induction of labor in groups A, B and C were 92.0%, 74.0% and 70.0%, respectively, P <0.05. Total labor during delivery was 10.4 ± 1.3, 18.7 ± 2 .3, 17.1 ± 2 .1, P <0.05. The blood loss and Apgar score three groups no difference, P> 0.05. Conclusion Mifepristone can not only effectively promote cervical ripening, but also improve the success rate of induction of labor, and the method is simple, safe and without side effects