神经梅毒是苍白密螺旋体侵袭中枢神经系统所致,见于梅毒感染任一阶段。晚期神经梅毒治疗效果差强人意,预后极差。需要尽早识别神经梅毒并进行积极治疗。然而神经梅毒临床表现纷繁复杂,早期诊断神经梅毒较为不易。当前各种社会人为因素增加诊断的难度。为增强早期识别神经梅毒,现报告1例高龄神经梅毒的临床表现、诊断和治疗等,并结合文献进行讨论。 Neurosyphilis is caused by Treponema pallidum invasion of the central nervous system, found in any stage of syphilis infection. Treatment of advanced neurosyphilis unsatisfactory outcome, poor prognosis. Neurological syphilis needs to be identified early and actively treated. However, the clinical manifestations of neurosyphilis complicated, early diagnosis of neurosyphilis is not easy. At present, various social human factors increase the difficulty of diagnosis. In order to enhance the early identification of neurosyphilis, 1 case of neurosyphilis was reported and its clinical manifestations, diagnosis and treatment were reported and discussed in the literature.