克隆氏病(Crohn)在我国较少见,而急性克隆氏病致二处游离穿孔则十分罕见,我院经手术、病理证实急性克隆氏病致二处穿孔1例,现报告如下。女,26岁,因四个月前无诱因发热,最高体温达41℃,伴寒战,对症治疗后体温降至正常。逐渐伴有腹痛,排便次数增多,6～8次/日,为稀红色便,有时有粘液。四肢水肿,疼痛,以膝、肘关节为著。发病来体重下降约30kg,在当地经用大剂量抗生素、激素、中药等治 Crohn’s disease is rare in our country, while acute Crohn’s disease caused by two free perforation is very rare, our hospital by surgery, pathology confirmed acute Crohn’s disease caused by two perforation in 1 case, are as follows. Female, 26 years old, had no incentive to fever four months ago and had a maximum body temperature of 41 ° C. With chills and symptomatic treatment, the body temperature dropped to normal. Gradually accompanied by abdominal pain, bowel movements increased, 6 to 8 times / day, it is a rare red, and sometimes mucus. Extremities edema, pain, knee, elbow for. The incidence of weight loss about 30kg, the local use of high doses of antibiotics, hormones, traditional Chinese medicine and other treatment