论文部分内容阅读
目的:研究利福平致急性间质性肾炎的诊断与治疗。方法:对29例(25～59岁)利福平致急性间质性肾炎的患者采用血管穿刺或动静脉外瘘,进行个体化血液透析(或腹膜透析)与药物治疗的效果进行了研究。结果:经透析和药物治疗后29名患者病情明显好转,症状逐渐消失,尿量增多、恢复正常,血肌酐(SCr)和尿素氮(BUN)分别由最高2091.3μmol·L-1、55mmol·L-1降至正常。结论:及时恰当地给予透析、药物等综合治疗利福平相关急性间质性肾炎,能取得满意的疗效。
Objective: To study the diagnosis and treatment of rifampin-induced acute interstitial nephritis. Methods: The effects of individual hemodialysis (or peritoneal dialysis) and drug therapy were studied in 29 patients (25-59 years) with rifampin-induced acute interstitial nephritis by means of vascular puncture or arteriovenous fistula. Results: After dialysis and drug treatment, the symptoms of 29 patients improved significantly, symptoms disappeared gradually, urine output increased and returned to normal. Serum creatinine (SCr) and urea nitrogen (BUN) increased from 2091.3μmol·L-1 to 15mmol·L -1 to normal. Conclusion: Appropriate treatment effects such as dialysis, drugs and other appropriate treatment of rifampin-related acute interstitial nephritis can be obtained timely and properly.