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目的:探究肾管状囊性癌的临床表现、病理特征、鉴别诊断及预后。方法:回顾1例肾管状囊性癌的诊疗过程,从国内外数据库搜索同类患者文献资料并进行统计分析。结果:肾管状囊性癌临床罕见,汇总国内外报道83例,筛选有效病例共51例进行统计学分析,结果显示肾管状囊性癌发病年龄18~94岁,平均(57.43±16.07)岁,男女发病率之比为8∶1,肿瘤大小0.2~17.0cm,平均(4.28±3.01)cm。以性别分组,男女发病年龄及肿瘤大小差异无统计学意义(P>0.5);以有无临床症状分组,发现有临床症状者发病年龄(39.40±16.24)显著低于无临床症状者(59.39±14.95),P=0.049。本资料1例肾管状囊性癌,病理观察及免疫组化与文献描述相符,肾切除术后随访19个月无复发及转移。结论:肾管状囊性癌好发于男性,临床表现与其他肾肿瘤相比无特异性,病理学及免疫组织化学检查为主要确诊方法,手术切除是主要治疗手段,预后良好,具有低度恶性潜能。
Objective: To investigate the clinical manifestations, pathological features, differential diagnosis and prognosis of renal tubular cystic carcinoma. Methods: To review the diagnosis and treatment of 1 case of renal tubular cystic carcinoma, search the literature of similar patients from domestic and foreign databases and make statistical analysis. Results: Tuberculous cystic carcinoma was rare in clinic. 83 cases were reported at home and abroad, and 51 cases were selected for statistical analysis. The results showed that the age of onset of renal tubular cystic carcinoma was 18-94 years, with an average of (57.43 ± 16.07) Male to female incidence ratio of 8: 1, tumor size 0.2 ~ 17.0cm, with an average (4.28 ± 3.01) cm. There were no significant differences in the age of onset of men and women and the size of tumor (P> 0.5). There was no significant difference in the age of onset of symptoms (39.40 ± 16.24) between the groups with or without clinical symptoms (59.39 ± 14.95), P = 0.049. This data 1 renal tubular cystic carcinoma, pathological observation and immunohistochemistry consistent with the literature description, no recurrence and metastasis after 19 months of follow-up of nephrectomy. CONCLUSIONS: Tubular cystic carcinoma occurs predominantly in men and has no specific clinical features compared with other renal tumors. Pathology and immunohistochemistry are the main diagnostic methods. Surgical resection is the primary treatment and has a good prognosis with low grade malignancy Potential.