人类IL-2具有T细胞生长因子(TCGF)的功能,可诱导激活的T细胞增殖.一般认为静止或激活的B细胞不能直接对IL-2起反应,但B细胞的增殖需要其他T细胞来源的淋巴因子,通常称为B细胞生长因子(BCGF).本文中,作者证明人类IL-2能有效地促进激活的人类B细胞增殖,并且是通过与激活的T细胞相同的表面受体发挥作用.为了证明对IL-2反应的细胞确实是B细胞而非污染的T细胞,作者利用去除E花环 Human IL-2 functions as a T-cell growth factor (TCGF) and induces proliferation of activated T cells It is generally accepted that resting or activated B cells do not respond directly to IL-2, but the proliferation of B cells requires additional T-cell sources , Commonly referred to as B-cell growth factor (BCGF) .In this paper, the authors demonstrate that human IL-2 can effectively promote the proliferation of activated human B cells and act through the same surface receptors as activated T cells To demonstrate that cells that respond to IL-2 are indeed B cells rather than contaminating T cells, the authors used a technique that removes E-garland