论文部分内容阅读
目的探讨局部及全身应用激素治疗慢性阻塞性肺病急性加重期临床疗效。方法选择我院2009年12月至2011年12月慢性阻塞性肺病患者80例,上述患者均为急性加重期。上述患者分为观察组和对照组。两组均给予吸氧、抗生素、支气管扩张剂、全身应用甲强龙。对照组采用以上治疗,观察组同时给予布地奈德雾化吸入。观察两组治疗前后肺功能改善情况。结果观察组治疗后FEV1和FEV1/FVC显著高于对照组治疗后,差异有统计学意义(P<0.05)。观察组总有效率显著高于对照组,差异有统计学意义(P<0.05)。结论局部及全身应用糖皮质激素类药联合治疗慢性阻塞性肺病急性加重期临床效果显著,值得借鉴。
Objective To investigate the clinical efficacy of topical and systemic hormone therapy in the treatment of acute exacerbation of chronic obstructive pulmonary disease. Methods Eighty patients with chronic obstructive pulmonary disease from December 2009 to December 2011 in our hospital were selected, all of whom were exacerbated. The above patients were divided into observation group and control group. Both groups were given oxygen, antibiotics, bronchodilators, systemic application of a strong dragon. The control group using the above treatment, the observation group also given budesonide inhalation. Observation of two groups before and after treatment to improve pulmonary function. Results The FEV1 and FEV1 / FVC of the observation group after treatment were significantly higher than those of the control group after treatment, the difference was statistically significant (P <0.05). The total effective rate of the observation group was significantly higher than that of the control group, the difference was statistically significant (P <0.05). Conclusion The combination of topical and systemic glucocorticoid drugs in the treatment of acute exacerbation of chronic obstructive pulmonary disease has a significant clinical effect and is worth learning from.