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目的探讨腹腔镜与开腹手术行全直肠系膜切除术(TME)治疗直肠癌的临床疗效。方法选择我院2006年1月至2010年3月收治的直肠癌患者136例,采用随机数字表法将患者分为研究组和对照组,每组各68例。研究组在腹腔镜下行TEM;对照组采用传统的开腹手术行TEM。对比两组患者术中出血量、术后切口感染率、术后排气时间、住院时间及两年生存率有无差别。结果与对照组相比,研究组的出血量较少(P<0.05),术后排气较早(P<0.05)、住院时间较短(P<0.05);术后切口感染率较低(P<0.05);两年生存率两组无明显差别(P>0.05)。结论腹腔镜与开腹手术行TME治疗直肠癌,腹腔镜在近期效果较开腹手术好,两种治疗方式的2年生存率相当。
Objective To investigate the clinical efficacy of total mesorectal excision (TME) for rectal cancer with laparoscopy and open surgery. Methods One hundred and sixty-six patients with rectal cancer admitted from January 2006 to March 2010 in our hospital were randomly divided into study group and control group, with 68 cases in each group. The study group underwent laparoscopic TEM; the control group underwent conventional open surgery TEM. Comparing the two groups of patients with intraoperative blood loss, postoperative incision infection rate, postoperative exhaust time, hospital stay and two-year survival rates were there any difference. Results Compared with the control group, the study group had less bleeding (P <0.05), postoperative exhaust earlier (P <0.05), hospital stay shorter (P <0.05), and postoperative incision infection rate was lower P <0.05). There was no significant difference in two-year survival between the two groups (P> 0.05). Conclusions Laparoscopy and open surgery were performed TME for rectal cancer. Laparoscopy was more effective in the near future than laparotomy. The two-year survival rates of the two treatments were similar.