透明细胞腺癌是来源于苗勒氏管的肿瘤,可发生在老年妇女的阴道、宫颈、子宫内膜和卵巢。近年来也观察到青年妇女发生阴道和宫颈透明细胞癌有所增加,多数曾在宫腔内接触过雌激素(DES)。虽然肿瘤的复发和致死通常与高分裂率和深部浸润有关,但在小的,表浅的或核分裂极少的肿瘤也偶 Clear cell adenocarcinoma is a Müllerian-derived tumor that can occur in the vagina, cervix, endometrium, and ovary of older women. In recent years, young women have also been observed to have increased vaginal and cervical clear cell carcinoma, most of whom have had estrogen (DES) exposure in the uterine cavity. Although tumor recurrence and lethality are usually associated with high rates of cleavage and deep infiltration, in small, superficial, or rarely mitotic tumors,