给小鼠一次性注射TNP-IgG 可使小鼠接触性致敏反应对抑制细胞和抑制因子的作用产生抵抗,作者发现,经注射TNP-IgG 之后,小鼠T 细胞在体外能产生一种抗原特异性抗抑制因子(Contras-uppressor factor,TesF)。经事先与TesF 共同培育后,免疫细胞能对随后加入的抑制性T 细胞或T细胞抑制因子产生耐受。TesF 为半抗原(TNP)所特异,能与抗I-J 结 One-time injections of TNP-IgG into mice resulted in resistance of mice to contact sensitization to inhibition of cells and suppressors. The authors found that mouse TNCs can produce an antigen in vitro after TNP-IgG injection Specific anti-inhibitory factor (Contras-uppressor factor, TesF). After prior incubation with TesF, immune cells are resistant to subsequent addition of suppressor T-cells or T-cell inhibitors. TesF is specific for the hapten (TNP) and can bind to anti-I-J