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目的了解住院患者精神药物的临床使用情况,为合理用药及科学管理提供参考。方法抽查1日住院患者处方,统计所有精神药物的用量及用药频率。分病种按限定日剂量(DDD)进行分析,病种以临床诊断为依据。结果住院患者精神分裂症占70%,情感障碍占18%,器质性精神障碍占5%,其它占7%。非典型抗精神病药使用占69%,传统抗精神病药使用占31%。新型抗抑郁药占94%,传统抗抑郁药占6%。结论传统抗精神病药用量大,副作用多,使用逐渐减少。非典型抗精神病药疗效肯定,副作用轻,患者依从性强,在使用中逐步占主导地位。新型抗抑郁药疗效肯定,不良反应少,有显著优势。精神药物药物利用指数(DUI)均未大于1,使用合理。
Objective To understand the clinical use of psychotropic drugs in hospitalized patients and provide references for proper medication and scientific management. Methods A random sample of patients admitted to hospital on the 1st prescription, statistics of all the amount of psychotropic drugs and frequency of medication. Sub-species according to the defined daily dose (DDD) analysis, the disease is based on clinical diagnosis. Results In-patient schizophrenia accounted for 70%, affective disorder accounted for 18%, organic mental disorders accounted for 5%, others accounted for 7%. Atypical antipsychotic use accounted for 69%, traditional antipsychotic use accounted for 31%. New antidepressants accounted for 94%, 6% of traditional antidepressants. Conclusion The traditional antipsychotic dosage, side effects and use gradually reduced. Atypical antipsychotic effect is positive, side effects, patient compliance, and gradually dominated in use. The new antidepressant efficacy is positive, fewer adverse reactions, there are significant advantages. Psychiatric drug use index (DUI) were not greater than 1, the use of reasonable.