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本文报告了1990年11月~1991年11月重庆地区261例发热待查病人嗜肺军团菌Ⅰ型(LegionliapueumophilaLP1)感染研究。作者采用ELISA法测定其血清抗体效价水平。结果表明,血清抗休效价阳性有95例,占总例数的36%。其中抗体效价<1:40有67例(70.5%),>1:80有16例(16.8%),>1:320有12例(12.6%)。在12人达到诊断标准(1:320)的病人中,有9人年龄在50岁以上、3人在50发以下。还用直接荧光免疫法对19例患者痰及支气管灌洗液作了LP1型抗原测定。结果表明,2名患者支气管灌洗液LP1抗原阳性。1名患者痰抗原阳性。本研究为临床军团菌感染的诊断和治疗提供了可靠依据。
This article reports the infection of LegionellapueumophilaLP1 in 261 patients with pyretic fever in Chongqing from November 1990 to November 1991. The authors used ELISA method to measure the serum antibody titers. The results showed that serum anti-titers were 95 positive cases, accounting for 36% of the total number of cases. Among them, 67 (70.5%) were antibody titers <1:40, 16 (16.8%) were> 1:80 and 12 (12.6%) were> 1: 320. Of the 12 patients who reached the diagnostic criteria (1: 320), nine were over 50 years of age and three were under 50. Direct immunofluorescence assay was also performed on LP1 antigen in sputum and bronchial lavage fluid of 19 patients. The results showed that two patients with LP1 antigen bronchial lavage positive. One patient had sputum antigen positive. This study provides a reliable basis for the diagnosis and treatment of clinical Legionella infection.