论文部分内容阅读
本文首次报道了利用(Ⅰ)苏丹兰GN、(Ⅱ)苏丹绿4 B、(Ⅲ)茜素绿啶、(Ⅵ)茜素紫3 B 和(Ⅴ)茜素亮紫R 五种氨基蒽醌染料用作亚硝酸法中的内指示剂,研究结果表明,它可在常温下,成功地应用于磺胺类、局部麻醉药(普鲁卡因、苯唑卡因),其它含有游离芳香胺基或经水解产生芳香胺基的药物(酞乙酰磺胺、酞磺胺噻唑)以及经水解、还原产生胺基的药物(氯霉素)的测定,获得满意结果,与英国药典法测定结果一致,并具有方法简便、迅速、终
In this paper, we report the first time that five aminoanthraquinones (Ⅰ), Sudan GN, (Ⅱ) Sudan Green 4 B, Alizarin Green (Ⅲ), Alizarin Red 3 B The dye is used as an internal indicator in the nitrous acid method. The results show that it can be successfully applied to sulfonamides, local anesthetics (procaine and benzocaine) at normal temperature, and other dyes containing free aromatic amine groups (Phthalethionamide, Phthalocyanine Sulfadiazole) and drugs (chloramphenicol) hydrolyzed and reduced to give amine groups, satisfactory results were obtained, which are in agreement with the results of the British Pharmacopoeia and have The method is simple, rapid, and final