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目的探讨蒙脱石散与巴曲酶联合治疗新生儿应激性溃疡出血的疗效。方法将93例应激性溃疡出血新生儿随机分成治疗组和对照组。2组基础治疗相同,治疗组在此基础上加用蒙脱石散与巴曲酶联合治疗,每日3次。治疗后观察临床疗效、出血停止时间,同时观察不良反应。结果治疗组总有效率为93.9%,止血时间为(1.26±0.68)d;对照组总有效率为79.5%,止血时间为(2.73±0.81)d。二组比较差异均有统计学意义(χ2=4.237,P<0.05;t=9.510,P<0.05),且无不良反应发生。结论蒙脱石散与巴曲酶联用治疗新生儿应激性溃疡出血效果显著。
Objective To investigate the curative effect of montmorillonite powder and batroxobin in the treatment of neonatal stress ulcer bleeding. Methods Ninety-three neonates with hemorrhagic stress ulcer were randomly divided into treatment group and control group. Two groups of the same basic treatment, the treatment group on the basis of montmorillonite plus batroxobin combination therapy, 3 times a day. After treatment, observe the clinical effect, bleeding stop time, while observing adverse reactions. Results The total effective rate was 93.9% and the bleeding time was (1.26 ± 0.68) d in the treatment group. The total effective rate in the control group was 79.5% and the bleeding time was (2.73 ± 0.81) days. The difference between the two groups was statistically significant (χ2 = 4.237, P <0.05; t = 9.510, P <0.05), and no adverse reactions occurred. Conclusion Montmorillonite powder and batroxobin treatment of neonatal stress ulcer bleeding effect.