用淋球菌聚合酶链反应诊断男性淋菌性尿道炎，６１例患者中９例作分泌物培养和ＰＣＲ，培养阳性２例，ＰＣＲ阳性５例；５２例先取尿道拭子作培养，后取始段晨尿作ＰＣＲ，培养阳性１例，ＰＣＲ阳性１８例．培养总阳性率４．９２％，ＰＣＲ总阳性率３７．８％，两者有显著性差异．笔者认为晨尿淋菌ＰＣＲ可作为一种敏感方法用于本病的诊断． Neisseria gonorrhoeae was diagnosed by gonococcal polymerase chain reaction in 9 of 61 patients with secretions and PCR, 2 were positive in culture and 5 were positive in PCR. Fifty-two of them were cultured in urethral swabs, Morning urine for PCR, culture positive in 1 case, PCR-positive in 18 cases. The total positive rate of culture was 4.92%, the total positive rate of PCR was 37.8%, there was a significant difference between the two. I believe morning urine PCR can be used as a sensitive method for the diagnosis of the disease.