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为探讨运动性低血睾酮与肾阳虚对骨骼肌α－ａｃｔｉｎ基因表达的影响是否相同，以长期大强度、较长时间游泳造成运动性低血睾酮，以０．５％腺嘌呤喂饲大鼠造成肾阳虚，并就两种状态下大鼠骨骼肌α－ａｃｔｉｎ基因的表达进行了探讨。结果表明：两种状态均出现血清睾酮浓度的下降，肾阳虚状态下的下降幅度远较运动性低血睾酮明显，运动性低血睾酮大鼠骨骼肌α－ａｃｔｉｎ基因表达与正常相比差异不大，而肾阳虚大鼠该基因表达则明显受抑。基于这些结果，可以认为两种状态在性腺轴功能紊乱方面存在一定的相同之处，但程度不同；肾阳虚通过抑制骨骼肌收缩蛋白基因表达可能影响大鼠骨骼肌的功能，运动性低血睾酮大鼠骨骼肌则未出现这种变化。可以推论：运动性低血睾酮是与本研究采用的肾阳虚模型差异很大的状态，在用治疗肾阳虚中药纠正运动性低血睾酮时应该慎用。
To explore whether exercise-induced hypokalemic testosterone and kidney yang deficiency have the same effect on α-actin gene expression in skeletal muscle, long-term high-intensity, long-term swimming resulted in exercise-induced hypokalemia and 0.5% adenine feeding Rats caused by kidney yang, and skeletal muscle α-actin gene expression in two states were discussed. The results showed that the serum testosterone concentration decreased in both of the two states, and the extent of decline in kidney-yang deficiency was much more than that in exercise-induced hypokalemia testosterone. Compared with the normal rats, the expression of α-actin in skeletal muscle of exercise- Not significant, while the gene expression of kidney yang rats was significantly inhibited. Based on these results, we can conclude that there are some differences between the two states in the gonadal axis dysfunction, but to a different degree. Kidney-yang deficiency may affect the function of skeletal muscle and hypomotility in rats by inhibiting the gene expression of skeletal muscle contractile protein Testosterone rat skeletal muscle does not appear this change. It can be inferred that exercise-induced hypokalemia is associated with a very different model of kidney-yang deficiency used in this study. It should be used with caution in the treatment of locomotor hypokalemia.