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对子宫内膜癌、非典型增生、单纯增生、增生期内膜及分泌期内膜共104例,分5组进行核仁区相关蛋白(AgNoRs)的研究。每个细胞核内AgNoRs颗粒平均数为内膜癌组>非典型增生组>单纯增生组>增生期内膜组>分泌期内膜组。各组间比较经统计学处理有显著性意义。本文提出AgNoRs计数在鉴别宫内膜良、恶性病变有显著意义,在不同程度的良性增生性病变中也有差异。故AgNoRs计数在宫内膜良、恶性病变诊断与鉴别诊断中具有重要参考价值。
A total of 104 cases of endometrial cancer, atypical hyperplasia, simple hyperplasia, proliferative endometrium and secretory endometrium were divided into 5 groups to study the nuclear related protein (AgNoRs). The average number of AgNoRs particles in each nucleus was endometrial cancer group> atypical hyperplasia group> simple hyperplasia group> proliferative endometrium group> secretory endometrium group. The comparison among groups was statistically significant. This paper presents AgNoRs count in the identification of benign and malignant endometrial lesions have significant significance, in varying degrees of benign proliferative lesions are also different. Therefore, the counting of AgNoRs in endometrial benign and malignant lesions diagnosis and differential diagnosis has important reference value.