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目的 :了解川芎嗪治疗肾综合症出血热的临床意义。方法 :将 2 42例肾综合症出血热 (HFRS)患者随机分为治疗组12 4例与对照组 118例 ,治疗组在常规治疗的基础上加用川芎嗪 80mg/d 1次静滴 ,疗程 3～ 5d。 结果 :与对照组相比 ,治疗组肾衰发生率低、尿蛋白消失早、PLT与BuN复常快、血与尿 β2 MG升高幅度低 (P <0 .0 1或P <0 .0 5 ) ,并发症减少(P <0 .0 5 ) ,治愈率提高。结论 :川芎嗪对肾综合症出血热 (HFRS)有较好疗效。
Objective : To understand the clinical significance of tetramethylpyrazine in the treatment of hemorrhagic fever with renal syndrome. METHODS: A total of 242 patients with hemorrhagic fever with renal syndrome (HFRS) were randomly divided into treatment group (124 cases) and control group (118 cases). The treatment group was treated with tetramethylpyrazine (80 mg/d) infusion on the basis of routine treatment. 3 ~ 5d. RESULTS: Compared with the control group, the incidence of renal failure was lower in the treatment group, urinary protein disappeared earlier, PLT and BuN were more frequent, blood and urine β2 MG increased less (P <0. 01 or P <0. 0 5) The complications decreased (P < 0.05) and the cure rate increased. Conclusion : Ligustrazine has a good effect on hemorrhagic fever with renal syndrome (HFRS).