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心钠素(ANP)具有强大的扩血管和利尿作用,但是迄今未见ANP直接扩张人体血管的实验报告.作者以体积描记法,观察静脉血流阻断条件下前臂血管床对α-人ANP(α-hANP)的反应.受试者为血压正常的16例健康志愿者,平均年龄28(22～48)岁.左臂供试验,右臂作对照.肘部和腕部各扎一条血压袖带,测定前臂血流量(FAF)前一分钟和测量中二带分别充气至40和50mmHg,暂时性阻断静脉血流.应力计固定于前臂上1/3处,联接体积描记仪,测定FAF.左臂肱动脉插管(16例),以备采血、测压和注入药物.左臂(7例)和右臂(4例)肘前静脉插管供采血之用.α-hANP剂
Atrial natriuretic peptide (ANP) has a strong vasodilator and diuretic effects, but so far no ANP direct report of human blood vessels to expand the experimental report by the author of plethysmography venous blood flow to observe the forearm vascular bed on α-human ANP (α-hANP) .The subjects were normal blood pressure in 16 healthy volunteers, the average age of 28 (22 to 48) years old, the left arm for the test, the right arm as a control elbow and wrist barbed a blood pressure Cuff, measured forearm blood flow (FAF) one minute before the measurement and the second zone were inflated to 40 and 50mmHg, temporarily blocking the venous flow.Stress gauge fixed in the upper arm 1/3, coupled plethysmography, determination The left arm (7 cases) and the right arm (4 cases) were anastomosed with anterior elbow vein for blood collection.α-hANP agents