论文部分内容阅读
探讨急性胰腺炎患者及正常对照组血、尿淀粉酶变化及血肌酐值，计算淀粉酶、肌酐廓清比率，确定其在急性胰腺炎时的诊断价值。用 Ｌｅｖｉｔｔ 提出的方法收集病人２ 小时尿，计尿量，同时抽静脉血，分别测定血清、尿淀粉酶和肌酐含量，并分别计算出淀粉酶廓清率（ Ｃａｍ） 、肌酐廓清率（ Ｃｃｒ） 及淀粉酶、肌酐廓清率比率（ Ｃａｍ／ Ｃｃｒ） 。结果： 急性胰腺炎患者血、尿淀粉酶较正常对照组明显增高，两组差异非常显著（ Ｐ ＜ ０ ．００１） ； Ｃａｍ 明显增高，两组差异非常显著（ Ｐ ＜ ０ ．００１） ； Ｃｃｒ 明显下降，两组差异显著（ Ｐ ＜ ０ ．０２） ；淀粉酶－ 肌酐廓清率比率明显增高（９３５ ±６５６） ，两组差异非常显著（ Ｐ ＜ ０００１） 。笔者认为，淀粉酶、肌酐廓清率比率对急性胰腺炎的诊断有意义，并认为其比单纯测定血、尿淀粉酶活性要好。
To investigate the changes of blood and urine amylase and serum creatinine in patients with acute pancreatitis and normal control group, and to determine the amylase and creatinine clearance ratio, and to determine its diagnostic value in acute pancreatitis. Levitt’s method was used to collect the urine and urine volume of patients for two hours and the venous blood was drawn at the same time. The levels of serum amylase, creatinine and amylase were measured respectively. The amylase clearing rate (Cam), creatinine clearance rate (Ccr) Amylase, creatinine clearance rate (Cam / Ccr). Results: The levels of blood and urine amylase in patients with acute pancreatitis were significantly higher than those in normal controls (P <0.001); the levels of Cam increased significantly in both groups (P <0.001); Ccr was significantly higher (P <0.01). The ratio of amylase to creatinine clearance rate was significantly higher (935 ± 656), the difference between the two groups was significant (P <0001). The author believes that the amylase, creatinine clearance rate of the diagnosis of acute pancreatitis is meaningful and that it is better than the simple determination of blood, urine amylase activity is better.