论文部分内容阅读
目的探讨金标法测定肌钙蛋白I(cTnI)对门诊、急诊急性心肌梗死(AMI)患者的诊断价值。方法对临床确诊患者75例,门诊急诊有相应临床症状而未确诊25例患者,用金标法测定患者血清中cTnI,严格按试剂说明书判断定性和半定量结果。结果检测的25例临床确诊患者中,阳性22例,占88%(半定量结果为:0.2～4.0 ng/ml),阴性3例,占12%(半定量结果<0.2 ng/ml)。检测的75例门诊有相应临床症状而未确诊患者中,cTnI阳性13例临床确诊均为AMI,占17.3%(半定量结果为:0.5～4.0 ng/ml);阴性62例,最后经临床确诊均为非AMI,占82.7%(半定量结果<0.2 ng/ml)。结论金标法测定肌钙蛋白I对急性心肌梗死的诊断具有更高的灵敏度和特异性,特别是对门、急诊,具有相应临床症状的患者,是一种较好的快速筛查手段。
Objective To investigate the diagnostic value of gold standard method for the determination of cTnI in outpatient and emergency patients with acute myocardial infarction (AMI). Methods 75 clinically diagnosed patients with clinically relevant clinical symptoms but no diagnosis of 25 patients with gold standard method for the determination of serum cTnI, in strict accordance with the reagent manual to determine the qualitative and semi-quantitative results. RESULTS: Of the 25 clinically diagnosed patients, 22 were positive, accounting for 88% (semiquantitative results: 0.2-4.0 ng / ml), negative in 3 cases, accounting for 12% (semiquantitative results <0.2 ng / ml). Of the 75 clinically diagnosed patients with undiagnosed clinical manifestations, 13 (13.3%) were diagnosed as cTnI positive (semiquantitative results: 0.5-4.0 ng / ml); the other 62 were negative and were clinically diagnosed All were non AMI, accounting for 82.7% (semiquantitative results <0.2 ng / ml). Conclusion The gold standard method for the determination of troponin I in the diagnosis of acute myocardial infarction with higher sensitivity and specificity, especially for the door, emergency, patients with the corresponding clinical symptoms, is a good rapid screening method.