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肺内细胞外基质(extracellular maxtnx, ECM)成分主要包括胶原、弹性蛋白、蛋白多糖及黏连糖蛋白等。尸检研究发现,早产儿慢性肺疾病(chronic lung disease, CLD)患儿肺组织病灶内胶原蛋白沉积水平与纤维化程度呈正相关,患儿支气管肺泡灌洗液(bronchoalveolar lavage fluid
Extracellular maxtnx (ECM) components in the lung mainly include collagen, elastin, proteoglycan and adhesion glycoprotein. An autopsy study found that there was a positive correlation between the level of collagen deposition and the degree of fibrosis in the lung tissue of children with chronic lung disease (CLD) in preterm infants. Bronchoalveolar lavage fluid