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目的观察胰岛素泵连续皮下胰岛素注射对 2型糖尿病患者强化血糖控制的效果。方法 2型糖尿病患者 2 6例 ,随机分成 2组 ,CSII组 1 2例 ,采用胰岛素泵连续皮下注射短效胰岛素。MSII组患者 1 4例 ,采用多次胰岛素注射法 ,在每日三餐前注射短效胰岛素 ,并在每晚睡前加注中效胰岛素。结果两组均能有效控制血糖达到较好的水平 ,CSII组需要的达标血糖时间 ,胰岛素用量及低血糖发生率明显减少。结论胰岛素泵强化治疗能较好的模拟胰岛素分泌的生理节律 ,更有效地控制高血糖 ,减少血糖的波动和低血糖的发生
Objective To observe the effect of continuous subcutaneous insulin injection of insulin pump on intensive glycemic control in type 2 diabetic patients. Methods Twenty-six patients with type 2 diabetes mellitus were randomly divided into 2 groups, 12 patients in CSII group. Subcutaneous injection of short-acting insulin with insulin pump. MSII group of 14 patients, using multiple insulin injections, short-acting insulin injections before the three meals a day, and in every night before bedtime with mid-dose of insulin. Results Both groups were able to effectively control blood glucose levels to achieve better levels of CSG required glycemic time, insulin dosage and incidence of hypoglycemia was significantly reduced. Conclusion Insulin pump intensive therapy can better simulate the physiological rhythm of insulin secretion, more effectively control hyperglycemia, reduce the fluctuation of blood glucose and hypoglycemia