近廿余年来,由于新技术的不断发展和应用,使我们能认识许多与遗传有关的血浆凝血因子缺陷病,并从不同的临床和实验室表现作出诊断,制订预防和治疗措施。本文参考近期文献,从遗传学角度对此类疾病加以概述。通常常见为一组凝血因子缺乏,但 In the past 20 years, due to the continuous development and application of new technologies, we have been able to recognize many genetic-related plasma coagulation factor deficiency diseases and to make diagnosis and treatment measures based on different clinical and laboratory findings. This article refers to recent literature to outline such diseases genetically. Commonly known as a group of clotting factors lacking, however