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豚鼠分别暴露于125 dB SPL 和132 dB SPL 的稳态白噪声中1h 后.即时、1、3、7、15和30 d进行螺旋器扫描电镜观察,发现主要是第3回和蜗顶螺旋器受损,表现为外毛细胞听毛肿胀、融合、倒伏、断裂和丧失,甚至外毛细胞缺如.暴露于132 dB 白噪声后即时有10 mm 耳蜗螺旋器受损,125 dB 为7 mm.前者有70%外毛细胞受损,后者为50%.噪声强度越大,螺旋器病变范围和外毛细胞受损数量增大,随存活时间延长而减轻.得到恢复的主要是轻度病变的外毛细胞,如静纤毛肿胀和融合,但中、重度损伤时静纤毛倒伏和消失未能恢复.白噪声暴露早期(125 dB 组暴露噪声后7 d,132 dB 组15 d),及时采用治疗措施的重要性.本文对噪声所致螺旋器损害的特点进行了讨论.
Guinea pigs were exposed to steady-state white noise at 125 dB SPL and 132 dB SPL, respectively, for 1 h. Spiral scanning electron microscopy was performed immediately, 1, 3, 7, 15, and 30 d, Damaged, manifested as swelling, fusion, lodging, rupture, and loss of outer hair cells even in absence of outer hair cells Immediate damage of 10 mm cochlear spiral exposed to 132 dB white noise, 125 dB at 7 mm. The former has 70% of the outer hair cells damaged, the latter is 50% .The greater the noise intensity, spiral lesions and the number of outer hair cell damage increased, with the survival time to reduce the recovery was mainly mild lesions Of the outer hair cells, such as static cilia swollen and fused, but failed to recover in the middle and severe injury.While the early exposure to white noise (7 days after 125 dB exposure, the 132 dB group for 15 days) The importance of treatment measures.This article discusses the characteristics of noise-induced spiral damage.