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目的总结膀胱癌伴发前列腺癌的临床特点,提高对膀胱癌伴发前列腺癌的认识。方法分析9例膀胱癌伴发前列腺癌患者的临床资料。结果 9例患者均采用全身麻醉下根治性膀胱前列腺切除术,术后病理证实均为膀胱癌伴发前列腺癌,膀胱癌病理分期:5例pT2N0M0、4例pT3N0M0;前列腺癌病理分期:3例pT1、4例pT2、2例pT3,Gleason评分4-8分;均未化疗,随访观察6例,前列腺癌内分泌治疗3例;随访6-78个月,前列腺特异性抗原(PSA)无进展5例,PSA进展4例,其中肿瘤广泛转移死亡1例。结论膀胱癌伴发前列腺癌临床少见,容易漏诊;男性膀胱癌患者围手术期间,行肛门指检、PSA检查、前列腺影像学检查,对于及时发现伴发前列腺癌是必要的。
Objective To summarize the clinical features of bladder cancer with prostate cancer and to raise awareness of bladder cancer with prostate cancer. Methods Nine cases of bladder cancer with prostate cancer were analyzed. Results All the 9 patients underwent radical prostatectomy under general anesthesia. Pathological examination confirmed bladder cancer with prostate cancer, pathological stage of bladder cancer: 5 cases of pT2N0M0 and 4 cases of pT3N0M0; 3 cases of pT1 , 4 cases of pT2, 2 cases of pT3, Gleason score of 4-8; no chemotherapy, follow-up observation of 6 cases, 3 cases of prostate cancer endocrine therapy; follow-up 6-78 months, prostate-specific antigen (PSA) , PSA progress in 4 cases, including extensive tumor death in 1 case. Conclusions Bladder cancer with prostate cancer is rare and missed. Bladder cancer patients with anus, PSA, and prostate imaging during perioperative period are necessary for timely detection of prostate cancer.