口腔宿主为幽门螺杆菌 (Ｈｐ)的存在提供各种适宜条件 ,常规根除Ｈｐ三联疗法对口腔Ｈｐ不敏感 ,本文就改善Ｈｐ诊断方法和探讨口腔中Ｈｐ的重要作用作一简要综述。一、幽门螺杆菌的发现及意义1893年 ,Ｂｉｚｚｏｚｅｒｏ[1] 首次报道在狗的胃腺内发现有一种螺旋形微生物 (Ｓｐ Oral host provides various suitable conditions for the presence of Helicobacter pylori (Hp). Hp triple therapy is not sensitive to oral Hp. A brief review is given in this paper on the improvement of Hp diagnostic methods and the exploration of the role of Hp in oral cavity. First, the discovery of Helicobacter pylori and its significance In 1893, Bizzozero [1] first reported in the dog’s stomach gland found a spiral microorganism (Sp