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无菌性化脓性脑膜炎(mèningite puriformeaseptique,MPA)在原因不明的细菌性脑膜炎的各种统计中占有一定的比例。1969年1月至1977年1月在 Claude Bernard 医院的传染病房观察了600例脑膜炎病人。其中100例是MPA,男性64例,女性36例;平均年龄34(3～88)岁诊断根据脑膜刺激征、脑脊液细胞增多(中性多核占大多数)和脑脊液培养72小时结果阴性。所有病人均作了仔细的细菌学检查,其中有几例还作了全套病毒学检查。这组病人均于1977年1月前入院,当时医院尚无对流免疫电泳作为常规诊断技术。结果 100例病人的最后诊断为细菌性脑膜炎57例,难以归类的脑膜炎23例,病毒性脑膜炎5例,颅内占位性病变10例,其他5例(化学性脑膜炎2例,亚急性细菌性心内膜炎性脑膜炎2例,狼疮性脑膜炎1例)。从上结果看出,细菌性脑膜炎的比例较大,颅内占位性病变也常以 MPA 的形式表现。因技术设备所
Aseptic meningitis meningitis (mèningite puriformeaseptique, MPA) account for a certain percentage of the various statistics of bacterial meningitis of unknown cause. Between January 1969 and January 1977, 600 meningitis patients were observed in the infectious ward at Claude Bernard Hospital. Of these, 100 were MPA, with 64 males and 36 females. The median age was 34 (3-88) years and was diagnosed according to meningeal irritation with increased cerebrospinal fluid cells (most of the multicellular nucleus) and CSF cultures for 72 hours. All patients were carefully bacteriological examination, of which a few have also made a full set of virological examination. This group of patients were admitted before January 1977, when there was no convective immuno-electrophoresis in the hospital as a routine diagnostic technique. Results The final diagnosis of 100 cases was bacterial meningitis in 57 cases, indistinguishable meningitis in 23 cases, viral meningitis in 5 cases, intracranial space-occupying lesions in 10 cases and other 5 cases (chemical meningitis in 2 cases , Subacute bacterial endocarditis meningitis in 2 cases, lupus meningitis in 1 case). From the above results, the proportion of bacterial meningitis larger, intracranial space-occupying lesions are often in the form of MPA. Due to technical equipment