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目的探讨食管小细胞癌(ESCC)淋巴结转移的相关危险因素。方法回顾性分析18例接受手术治疗的ESCC患者临床及病理资料,分析淋巴结转移相关因素。结果淋巴结转移与肿瘤形态、肿瘤部位、病变长度、肿瘤浸润深度分期和脉管内瘤栓密切相关(P<0.05)。胸上段和胸下段肿瘤淋巴结转移高于胸中段(P<0.05)。病变长度≥2cm肿瘤淋巴结转移高于病变长度<2cm者(P<0.05)。T3+T4期肿瘤淋巴结转移高于T1+T2期(P<0.05)。结论肿瘤形态、肿瘤部位、病变长度、肿瘤浸润深度及脉管内瘤栓是影响ESCC淋巴结转移的危险因素。
Objective To investigate the risk factors of lymph node metastasis in esophageal small cell carcinoma (ESCC). Methods Retrospective analysis of 18 cases of ESCC patients undergoing surgical treatment of clinical and pathological data, analysis of lymph node metastasis-related factors. Results The lymph node metastasis was closely related to tumor morphology, tumor location, lesion length, depth of tumor invasion and vascular tumor thrombus (P <0.05). Lymph node metastasis in the upper thoracic and lower thoracic segments was higher than that in the mid-thoracic segments (P <0.05). Lesion length> 2cm tumor lymph node metastasis higher than the lesion length <2cm (P <0.05). Tumor metastasis of T3 + T4 stage was higher than T1 + T2 stage (P <0.05). Conclusion The tumor morphology, tumor location, lesion length, tumor invasion depth and vascular tumor thrombus are the risk factors of lymph node metastasis in ESCC.