选用D-半乳糖胺、硫代乙酰胺、四氯化碳三个肝损伤毒物构建肝损伤模型,研究了关龙胆地上部分对于不同机制引起的肝损伤的保肝作用。实验结果表明关龙胆地上部分有保肝作用,可降低各种肝损伤模型的ALT(谷丙转氨酶)、AST(谷草转氨酶)、AKP(碱性磷酸酶)等,从而证明了关龙胆地上部分有一定药用价值,用全草取代地下部分入药有一定的可行性。 D-galactosamine, thioacetamide and carbon tetrachloride were used to establish a liver injury model and to study the protective effect of the above-ground part of gentian against liver injury caused by different mechanisms. The experimental results show that the above-ground part of gentian has hepatoprotective effects, which can reduce ALT (alanine aminotransferase), AST (aspartate aminotransferase) and AKP (alkaline phosphatase) in various liver injury models, Some have some medicinal value, with the whole grass to replace the underground part of medicine has a certain feasibility.