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为探讨Ⅱ型糖尿病合并缺血性心脏病患者的心率变异性及其临床意义，应用２４小时动态心电图监测７８例Ⅱ型糖尿病患者，并与４８例年龄、性别配对的正常人比较。结果显示Ⅱ型糖尿病患者１０项时域分析指标及心率变异指数均比正常人明显减低，最小心率比正常人增快；合并缺血性心脏病患者心率变异指数减低的阳性率明显高于同组其它Ⅱ型糖尿病患者。提示Ⅱ型糖尿病患者植物神经损害，迷走神经张力减低，心率变异性减低，而且其心率变异性减低程度与心脏损害程度有关。
To investigate the heart rate variability and its clinical significance in patients with type 2 diabetes mellitus complicated with ischemic heart disease, 78 patients with type 2 diabetes mellitus were monitored by 24-hour ambulatory electrocardiogram and compared with 48 age-matched and matched-sex normal subjects. The results showed that 10 time-domain analysis indexes and heart rate variability index in type 2 diabetic patients were significantly lower than those in normal subjects, and the minimum heart rate was faster than that in normal subjects. The positive rate of heart rate variability index in patients with ischemic heart disease was significantly lower than that in the same group Other type II diabetes patients. It suggests that autonomic nerve damage, vagal tone decrease and heart rate variability decrease in type 2 diabetic patients, and the extent of heart rate variability is related to the extent of heart damage.