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本文报道346例慢性阻塞性肺疾患病人常规通气功能、最大呼气流速—容量曲线和闭合气量的综合研究,并与784例正常人作了比较;各项结果均数并与自身预计值均数比较,提示了这些检查对发现COPD的肺功能异常有肯定价值。253例慢性支气管炎有/无肺气肿病人,于不同病程和不同痰量时常规通气功能的比较表明,随病程增加,通气功能逐渐减退,而MVV10年以下与10年以上即有显著差别,提示慢性支气管炎病程达10年后,多数病人即有发展到肺气肿的可能。随着痰量增加,加重通气功能损害,提出积极消炎、祛痰等治疗对改善肺功能的重要意义。常规通气功能、MEFV曲线和CV的单项阳性率和成对资料比较结果表明,V_(50)阳性率最高,通气功能较V_(中牛)和CV为优;通气功能中以FEV_1、PFR和MVV为好。FVC和CV最不敏感。故认为早期发现COPD病人的肺功能损害,用反映气道流速的测试方法比用反映容量的测试方法为敏感。
This article reports 346 patients with chronic obstructive pulmonary disease in patients with routine ventilation function, the maximum expiratory flow volume-volume curve and the closed volume of a comprehensive study and 784 normal subjects were compared; the results of all the mean and its expected value Comparisons suggest that these tests are of value in identifying pulmonary dysfunction in patients with COPD. 253 cases of chronic bronchitis with / without emphysema in patients with different duration and different sputum volume routine ventilation function comparison shows that with the increase of duration, ventilation function gradually decreased, and MVV 10 years and 10 years or more there is a significant difference, Prompt chronic bronchitis course of up to 10 years, most patients have the potential to develop emphysema. With the increase of sputum volume, aggravating the damage of ventilatory function, put forward the positive anti-inflammatory, expectorant and other treatment of the importance of improving lung function. The results showed that the positive rate of V_ (50) was the highest, and the ventilatory function was superior to V_ (middle cow) and CV. The ventilation function of FEV_1, PFR and MVV As well FVC and CV are the least sensitive. Therefore, early detection of COPD patients with lung function damage, with a test method that reflects the airway flow rate than the use of capacity-sensitive test method is sensitive.